Volume 4, Issue 4, December 2019, Page: 98-103
Thymic Neuroendocrine Tumour Results Cushing’s Syndrome
Taher Manzary, Department of Endocrinology, Tabriz University of Medical Sciences, Tabriz, Iran
Amir Teimouri Dereshgi, Department of Surgery, Tabriz University of Medical Sciences, Tabriz, Iran
Vahideh Sadra, Department of Endocrinology, Tabriz University of Medical Sciences, Tabriz, Iran
Ali Jamshidi Fard, Department of Endocrinology, Tabriz University of Medical Sciences, Tabriz, Iran
Leila Teimouri Dereshgi, Department of Pediatrics, Tabriz University of Medical Sciences, Tabriz, Iran
Touba Tarvirdizadeh, Department of Internal Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Received: Aug. 5, 2019;       Accepted: Nov. 5, 2019;       Published: Nov. 12, 2019
DOI: 10.11648/j.ijde.20190404.12      View  438      Downloads  69
Background: Thymic Neuroendocrine Tumor (TNET) is a rare clinical condition with approximate incidence rate of 2–5%. Carcinoid tumor of thymus with Cushing’s syndrome (CS) is also a rare co-morbid condition. Case information: Here we report a case of a 22-year-old gentleman presented with uncommon features suggestive of CS. He was evaluated and diagnosed with ectopic Adrenocorticotropic hormone (ACTH)–dependent CS due to a TNET. Results: Extensive thymectomy was performed and histopathology confirmed the diagnosis of thymic carcinoma with neuroendocrine differentiation and local and pericardial invasion. Conclusion: Thymic carcinomas may present with symptoms due to mass effect but Cushing syndrome is the most common endocrine manifestation of these tumors. Surgery is the most effective treatment of thymic carcinoma, although chemotherapy and radiotherapy also have been reported to be effective in some cases.
Cushing's Syndrome, Thymic Carcinoma, Neuroendocrine Tumor
To cite this article
Taher Manzary, Amir Teimouri Dereshgi, Vahideh Sadra, Ali Jamshidi Fard, Leila Teimouri Dereshgi, Touba Tarvirdizadeh, Thymic Neuroendocrine Tumour Results Cushing’s Syndrome, International Journal of Diabetes and Endocrinology. Vol. 4, No. 4, 2019, pp. 98-103. doi: 10.11648/j.ijde.20190404.12
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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